| Rank | Company Name | Sales Growth % | Description |
| 1 | Mazzella Companies | 252% | The company primarily operates in the management of companies and enterprise companies industry. |
| 2 | Safeguard Properties, LLC | 146% | Founded in 1990 by Robert Klein, Safeguard Properties is the largest field services company in the U.S. |
| 3 | Great Lakes Petroleum Co. | 129% | Great Lakes Petroleum is a fuel transportation company utilizing innovative logistics & tank technology via Smart Tank, a wireless fuel management system. |
| 4 | Emergency Medicine Physicians, Ltd. | 115% | EMP's residency-trained, board-certified physicians treat 3 million Emergency Department patients nationwide. |
| 5 | MobilityWorks | 98% | MobilityWorks is the largest retailer of adaptive vehicles and commercial vans for wheelchair transportation. |
| 6 | Hyland Software, Inc. | 98% | Hyland Software is a leading provider of enterprise content management solutions. |
| 7 | Dealer Tire, LLC | 82% | Dealer Tire partners with automakers to design and manage their dealership tire programs. |
| 8 | Saber Healthcare Group LLC | 73% | Provides respectful, compassionate, high quality care to the people of our communities. |
| 9 | Fairmount Santrol | 68% | Fairmount Santrol is one of North America's largest producers of industrial sand and resin-coated products. |
| 10 | National Interstate Insurance Company | 65% | National Interstate is a specialty property and casualty insurance company focused on the transportation industry. |
| 11 | Family Heritage Life Insurance Company of America | 48% | Marketer of supplemental health insurance products including cancer intensive care, heart, accident, hospital indemnity and life insurance. |
| 12 | Tradex International, Inc. | 40% | Tradex International is a leading supplier of disposable gloves and apparel. |
See the 2013 Weatherhead 100 Winners and the 2013 Upstart Winners.